SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004].
This track shows known protein-coding and non-protein-coding genes
for organisms other than marmoset, taken from the NCBI RNA reference
sequences collection (RefSeq). The data underlying this track are
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undergone: predicted (light), provisional (medium), reviewed (dark).
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The RNAs were aligned against the marmoset genome using blat; those
with an alignment of less than 15% were discarded. When a single RNA aligned
in multiple places, the alignment having the highest base identity was
identified. Only alignments having a base identity level within 0.5% of
the best and at least 25% base identity with the genomic sequence were kept.
This track was produced at UCSC from RNA sequence data
generated by scientists worldwide and curated by the
NCBI RefSeq project.
BLAT--the BLAST-like alignment tool.
Genome Res. 2002 Apr;12(4):656-64.
PMID: 11932250; PMC: PMC187518
Pruitt KD, Brown GR, Hiatt SM, Thibaud-Nissen F, Astashyn A, Ermolaeva O, Farrell CM, Hart J,
Landrum MJ, McGarvey KM et al.
RefSeq: an update on mammalian reference sequences.
Nucleic Acids Res. 2014 Jan;42(Database issue):D756-63.
PMID: 24259432; PMC: PMC3965018
Pruitt KD, Tatusova T, Maglott DR.
NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins.
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D501-4.
PMID: 15608248; PMC: PMC539979