wuhCor1 Mutations that confer drug resistance (Anna Niewiadomska, BV-BRC) (D483Y)
Mutation: D483Y
Position: NC_045512v2:14890-14892
Genomic Size: 3
View DNA for this feature (wuhCor1/SARS-CoV-2)

Reference genome nucleotides GAT
Mutated nucleotides TAT
Description Remdesivir failure with SARS-CoV-2 RNA-dependent RNA-polymerase mutation in a B-cell immunodeficient patient with protracted Covid-19. We report the occurrence of a mutation in the RdRP (D484Y) following failure of remdesivir in a 76-year-old woman with a
References Martinot et al. (2020)
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Data last updated at UCSC: 2022-07-01 11:52:39


This track lists amino acid mutations that are known to confer drug resistance against Remdesivir, Sotrovimab, and Nirmatrelvir (Paxlovid). They were sourced with permission from Paul Gordon's website at the University of Calgary and Anna Niewiadomska from the J. Craig Venter Institute, manually input by Max Haeussler.

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Thanks to Anna Niewiadomska from the BV-BRC team at the J. Craig Venter Institute for converting these to coordinates.