Description

These tracks represent the experimentally validated coding and non-coding promoters generated by EPD for H. sapiens.

Display Conventions and Configuration

Each element in these tracks is a representation of the promoter sequence presented in the EPD viewer page (here a non-coding example). Following this convention, the narrow part of the elements represents the 49 bp upstream of the annotated transcription start site (TSS) whereas the thick part represents the TSS plus the 10 bp downstream. The relative position of the thick and thin parts define the orientation of the promoter.

Methods

For a description of the methodology and principles used by EPD to predict TSSs, refer to Dreos et al. (2013) in the References section below. A more detailed description of how this data was generated can be found here.

Credits

Data was generated by the EPD team at the Swiss Institute of Bioinformatics (Dreos et al. 2013). For inquiries, please contact us using the online form here or post a message on philipp.bucher@epfl.ch.

References

Dreos R, Ambrosini G, Perier RC, Bucher P. EPD and EPDnew, high-quality promoter resources in the next-generation sequencing era. Nucleic Acids Res. 2013 Jan 1;41(D1):D157-64. PMID: 23193273.