The miRNA track shows microRNAs from
Display Conventions and Configuration
Mature miRNAs (miRs) are represented by
thick blocks. The predicted stem-loop portions of the primary transcripts
are indicated by thinner blocks. miRNAs in the sense orientation are shown in
black; those in the reverse orientation are colored grey. When a single
precursor produces two mature miRs from its 5' and 3' parts, it is displayed
twice with the two different positions of the mature miR.
To display only those items that exceed a specific unnormalized score, enter
a minimum score between 0 and 1000 in the text box at the top of the track
Mature and precursor miRNAs from the miRNA Registry were
aligned against the genome using blat.
The extents of the precursor sequences were not generally known, and were
predicted based on base-paired hairpin structure.
miRBase is described in Griffiths-Jones, S. et al. (2006).
The miRNA Registry is
described in Griffiths-Jones, S. (2004) and Weber, M.J. (2005) in the
References section below.
This track was created by Michel Weber of
Laboratoire de Biologie Moléculaire Eucaryote,
CNRS Université Paul Sabatier
(Toulouse, France), Yves Quentin of Laboratoire de Microbiologie et Génétique
Moléculaires (Toulouse, France) and Sam Griffiths-Jones of
The Wellcome Trust Sanger Institute
When making use of these data, please cite:
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ.
miRBase: microRNA sequences, targets and gene nomenclature.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4.
PMID: 16381832; PMC: PMC1347474
The microRNA Registry.
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D109-11.
PMID: 14681370; PMC: PMC308757
New human and mouse microRNA genes found by homology search.
FEBS J. 2005 Jan;272(1):59-73.
The following publication provides guidelines on miRNA annotation:
Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X,
Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M et al.
A uniform system for microRNA annotation.
RNA. 2003 Mar;9(3):277-9.
PMID: 12592000; PMC: PMC1370393
For more information on blat, see
BLAT - the BLAST-like alignment tool.
Genome Res. 2002 Apr;12(4):656-64.
PMID: 11932250; PMC: PMC187518