The subtracks of this track show mutations that lead to escape from patient serum antibodies or monoclonal
antibodies. Most of the mutations assayed were in the receptor binding domain (RBD) of the S protein.
The data shown here were imported from different studies, listed below. The
Bloom lab papers used deep mutational scanning data to measure the effect of all
possible mutations in the Spike RBD using a yeast surface display system.
For the Bloom lab data, we show just a summary of the data. Better and detailed structural
visualizations are available from the authors via dms-view using the following links:
10 monoclonal antibodies,
4 treatment antibodies.
To view the full description, click here.