is a web resource that provides predictions of biological targets of microRNAs by
searching for the presence of sites that match the seed region of each miRNA.
The TargetScan browser tracks show conserved mammalian microRNA regulatory target sites
for conserved microRNA families in the 3' UTR regions of human Refseq Genes.
Thanks to George Bell of
Bioinformatics and Research Computing at the Whitehead
Institute for providing this annotation, which was generated in collaboration
with the labs of David Bartel and Chris Burge.
Additional information on microRNA target prediction is available on the
The raw data can be explored interactively with the Table Browser,
or the Data Integrator. For automated analysis, the data may
be queried from our REST API. Please refer to our
mailing list archives
for questions, or our Data Access FAQ for more
Data is also freely available on the
Agarwal V, Bell GW, Nam JW, Bartel DP.
Predicting effective microRNA target sites in mammalian mRNAs.
Elife. 2015 Aug 12;4.
PMID: 26267216; PMC: PMC4532895
Garcia DM, Baek D, Shin C, Bell GW, Grimson A, Bartel DP.
Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and
Nat Struct Mol Biol. 2011 Sep 11;18(10):1139-46.
PMID: 21909094; PMC: PMC3190056
Friedman RC, Farh KK, Burge CB, Bartel DP.
Most mammalian mRNAs are conserved targets of microRNAs.
Genome Res. 2009 Jan;19(1):92-105.
PMID: 18955434; PMC: PMC2612969
Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP.
MicroRNA targeting specificity in mammals: determinants beyond seed pairing.
Mol Cell. 2007 Jul 6;27(1):91-105.
PMID: 17612493; PMC: PMC3800283
Lewis BP, Burge CB, Bartel DP.
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are
Cell. 2005 Jan 14;120(1):15-20.