This track displays the Human Body Map lincRNAs (large intergenic non
coding RNAs) and TUCPs (transcripts of uncertain coding potential), as well as their
expression levels across 22 human tissues and cell lines. The Human Body Map catalog was generated
by integrating previously existing annotation sources with transcripts that were de-novo assembled
from RNA-Seq data. These transcripts were collected from ~4 billion RNA-Seq reads across 24 tissues
and cell types.
Expression abundance was estimated by Cufflinks (Trapnell et al., 2010) based on RNA-Seq.
Expression abundances were estimated on the gene locus level, rather than for each transcript
separately and are given as raw FPKM. The prefixes tcons_ and tcons_l2_ are used to describe
lincRNAs and TUCP transcripts, respectively. Specific details about the catalog generation and data
sets used for this study can be found in Cabili et al (2011). Extended
characterization of each transcript in the human body map catalog can be found at the Human lincRNA
Expression abundance scores range from 0 to 1000, and are displayed from light blue to dark blue
The body map RNA-Seq data was kindly provided by the Gene Expression
Applications research group at Illumina.
Cabili MN, Trapnell C, Goff L, Koziol M, Tazon-Vega B, Regev A, Rinn JL.
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and
Genes Dev. 2011 Sep 15;25(18):1915-27.
PMID: 21890647; PMC: PMC3185964
Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, Salzberg SL, Wold BJ, Pachter
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform
switching during cell differentiation.
Nat Biotechnol. 2010 May;28(5):511-5.
PMID: 20436464; PMC: PMC3146043