◀ Back to RHOA
RHOA — WNT5A
Text-mined interactions from Literome
Zhu et al., PloS one 2012
(Breast Neoplasms) :
We showed here that
Wnt5a activated Dvl2, Daam1 and
RhoA , and promoted migration of breast cancer cells, which was, however, abolished by Secreted Frizzled related protein 2 ( sFRP2 ) pretreatment ... Dominant negative Dvl2 mutants or Dvl2 siRNA significantly decreased
Wnt5a induced
Daam1/RhoA activation and cell migration ... Ectopic expression of N-Daam1, a dominant negative mutant, or Daam1 siRNA remarkably inhibited
Wnt5a induced
RhoA activation, stress fiber formation and cell migration
Liu et al., Cell Signal 2013
(Stomach Neoplasms) :
Additionally, GSK3ß siRNA remarkably inhibited
Wnt5a induced
RhoA activation, stress fiber formation and cell migration
Zhu et al., Cell Signal 2013
(Breast Neoplasms) :
However, we found here that
RhoA activation was not
enhanced by
Wnt5a in breast cancer cells MCF-7
Wang et al., PloS one 2013
:
Instead of activating the canonical Wnt signal pathway in hDPCs,
Wnt5a stimulation induced activation of the JNK signal in a
RhoA dependent or independent manner