Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570629)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ IL1A ▸ BCL6 ▸
BCL3 ▸ BCL9 ▸ DIABLO ▸ BCL5 ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK15 ▸ MAPK4 ▸ MAPK14 ▸ MAPK6 ▸ MAPK10 ▸ MAPK12 ▸ MAPK8 ▸
MAPK7 ▸ MAPK13 ▸ MAPK11 ▸ MAPK9 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ CAPN10 ▸ DNTT ▸
CAPN15 ▸ CAPN9 ▸ CAPN2 ▸ CAPN7 ▸ CAPN12 ▸ IL18 ▸ CAPN11 ▸
CAPN14 ▸ CAPN6 ▸ CAPN5 ▸ CAPN8 ▸ CAPN13 ▸ CASP6 ▸ CAPN3 ▸
FADD ▸ CASP14 ▸ CASP16 ▸ CASP4 ▸ CASP10 ▸ CASP7 ▸ CASP5 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP9 ▸ MMP2 ▸ MMP3 ▸ MMP12 ▸
MMP11 ▸ JUN ▸ MMP14 ▸ MMP15 ▸ MMP24 ▸ MMP13 ▸ MMP8 ▸
MMP27 ▸ MMP26 ▸ NLRP3 ▸ MMP25 ▸ MMP19 ▸ MMP16 ▸ MMP21 ▸
MMP1 ▸ MMP20 ▸ MMP7 ▸ MMP28 ▸ MMP17 ▸ CDKN1A ▸ MMP10 ▸
PDCD5 ▸ PDCD11 ▸ PDCD4 ▸ PDCD7 ▸ RNF19A ▸ PDCD10 ▸ PDCD6 ▸
PDCD1 ▸ PDCD2 ▸ CFLAR ▸ CYCS ▸ NA ▸ IGF1 ▸ PCBD1 ▸
ANXA5 ▸ TGFB1 ▸ AHSA1 ▸ PIK3R1 ▸ INS ▸ PIK3CA ▸ HLA-DRB1 ▸
MPZ ▸ PRKCD ▸ NLRC4 ▸ EPO ▸ MYLIP ▸ PI3 ▸ VEGFA ▸
DDIT3 ▸ TAT ▸ PCNA ▸ IL6 ▸ NOS2 ▸ GRAP2 ▸ DFFA ▸
PRDX2 ▸ GSK3B ▸ TNFRSF1A ▸ CTSB ▸ DISC2 ▸ NGF ▸ PAK2 ▸
IL8 ▸ DISC1 ▸ BIRC2 ▸ EGF ▸ SOD1 ▸ CRK ▸ CTNNB1 ▸
EIF2AK2 ▸ CAST ▸ IL4 ▸ PTGS2 ▸ BID ▸ DFFB ▸ LEP ▸
NOS1 ▸ DNASE2 ▸ ABL1 ▸ ALPI ▸ DNASE1 ▸ P2RX7 ▸ IRF1 ▸
ROCK1 ▸ APP ▸ FOS ▸ MYC ▸ HGF ▸ SOD2 ▸ CAT ▸
HTRA2 ▸ CDK2 ▸ IFNB1 ▸ BCR ▸ CTSD ▸ BDNF ▸ MAP3K1 ▸
APEH ▸ IL16 ▸ IFI27 ▸ TCF4 ▸ UPK3B ▸ NOD2 ▸ RAC1 ▸
HSPA5 ▸ TCF19 ▸ RIPK1 ▸ BMP1 ▸ TCF20 ▸ TLR2 ▸ TCF21 ▸
IL10 ▸ FGF2 ▸ CSF2 ▸ TCF12 ▸ NOS3 ▸ TCF24 ▸ GAL ▸
TCF23 ▸ BMP4 ▸ NFKBIA ▸ TCF7 ▸ TCF3 ▸ TCF15 ▸ TCF25 ▸
BIRC3 ▸ PRKDC ▸ SOD3 ▸ APOB ▸ BIRC7 ▸ HDAC2 ▸ NOX1 ▸
GZMB ▸ CD8A ▸ POLDIP2 ▸ HDAC1 ▸ CSF3 ▸ MAP2K1 ▸ NLRP1 ▸
STAT1 ▸ ADCYAP1 ▸ IL2 ▸ ITIH4 ▸ TLR3 ▸ CDC73 ▸ HMGB1 ▸
BAD ▸ MAGT1 ▸ NOX4 ▸ AIM2 ▸ CA2 ▸ ATP5O ▸ ARSK ▸
TLR4 ▸ PPARA ▸ LMNB1 ▸ PML ▸ AGTR1 ▸ IL33 ▸ TLR7 ▸
PRNP ▸ PAF1 ▸ RAD51 ▸ NOX3 ▸ BMP10 ▸ CDK5 ▸ HPR ▸
BMP7 ▸ PPP2R1A ▸ NOD1 ▸ ENDOG ▸ BMP2 ▸ IL5 ▸ BMP15 ▸
LEO1 ▸ CD79A ▸ PPP2CA ▸ CARD8 ▸ TLR5 ▸ MST1 ▸ IL7 ▸
NOX5 ▸ APC ▸ PDLIM7 ▸ KRT18 ▸ IL3 ▸ SMPD2 ▸ IL11 ▸
BMP3 ▸ RB1 ▸ STAT3 ▸ PPP2R2B ▸ BMP6 ▸ BMP5 ▸ SNAP25 ▸
WDR61 ▸ RIPK2 ▸ CTR9 ▸ HSPB1 ▸ MAP2K2 ▸ CREB5 ▸ ICAM1 ▸
GP6 ▸ ANGPT1 ▸ JAK2 ▸ ARID1A ▸ BOC ▸ RBBP7 ▸ SMARCA4 ▸
LMNB2 ▸ CCDC88A ▸ BIRC6 ▸ IL15 ▸ PLCG1 ▸ TNFRSF1B ▸ ACTL6A ▸
TLR8 ▸ IL24 ▸ SMARCB1 ▸ GP5 ▸ PGP ▸ CREB3 ▸ LPA ▸
IL21 ▸ FOXO3 ▸ SMARCC1 ▸ ABCC6 ▸ CDH1 ▸ EIF2S1 ▸ HIF1A ▸
WAS ▸ PTX3 ▸ SMARCA2 ▸ SMARCC2 ▸ ANGPT2 ▸ IL20 ▸ ANXA1 ▸
IL25 ▸ TXN ▸ SMARCD1 ▸ NPS ▸ CSE ▸ EGFR ▸ SYK ▸
PTX4 ▸ GSN ▸ RBBP4 ▸ GP9 ▸ TLR10 ▸ IGF2 ▸ CDC6 ▸
MET ▸ SMARCE1 ▸ HTT ▸ TLR1 ▸ RIPK3 ▸ CXCL9 ▸ TRAF6 ▸
CREB1 ▸ GP2 ▸ CD4 ▸ SMARCD2 ▸ MUC2 ▸ MUC1 ▸ PLD1 ▸
IL22 ▸ MUC6 ▸ LYN ▸ PRKCA ▸ GATA1 ▸ MDM2 ▸ MEFV ▸
MUC4 ▸ CDK8 ▸ KDR ▸ RRAS ▸ SMPD1 ▸ CARD6 ▸ PPARG ▸
MUC12 ▸ IKBKB ▸ MUC17 ▸ ACHE ▸ CARD9 ▸ MSC ▸ IL34 ▸
TLR6 ▸ PTEN ▸ RENBP ▸ IL9 ▸ MUC16 ▸ BRCA1 ▸ MUC20 ▸
MUC13 ▸ ROCK2 ▸ IRF3 ▸ RAF1 ▸ IL26 ▸ SP1 ▸ CD79B ▸
PAK1 ▸ HSPD1 ▸ MUC7 ▸ UCN ▸ IL27 ▸ SYT1 ▸ MUC8 ▸
STX1A ▸ IL13 ▸ IL32 ▸ MUC21 ▸ CARD11 ▸ TOP1 ▸ CCND1 ▸
IL31 ▸ TLR9 ▸ BECN1 ▸ IL37 ▸ CDA ▸ IL19 ▸ MUC19 ▸
TRAF1 ▸ MUC22 ▸ MUC15 ▸ HMOX1 ▸ CARD18 ▸ NPM1 ▸ ATF2 ▸
PANX1 ▸ CDK4 ▸ PLD2 ▸ CD47 ▸ CEP68 ▸ PRKACG ▸ WNK1 ▸
CCR7 ▸ E2F1 ▸ MPST ▸ PRKACB ▸ SLC9A1 ▸ CCL2 ▸ CEP250 ▸
PRKAR1B ▸ CARD10 ▸ ADIPOQ ▸ GDNF ▸ H2AFX ▸ ZGLP1 ▸ NTF3 ▸
CALM3 ▸ ME2 ▸ BIRC5 ▸ PEA15 ▸ PRKAG1 ▸ PTHLH ▸ ARC ▸
CEP85 ▸ TIMP3 ▸ CARD14 ▸ SOAT1 ▸ CARD17 ▸ PNPLA2 ▸ SLCO6A1 ▸
ALB ▸ TRAF2 ▸ CEP170 ▸ PTK2 ▸ VDAC1 ▸ CEP104 ▸ VIMP ▸
GUCY2D ▸ BCL2L12 ▸ PRKAB1 ▸ PRKAR2A ▸ SLC17A5 ▸ SKP1 ▸ PPP1R3A ▸
PRKCG ▸ IRF4 ▸ CEP128 ▸ GRB10 ▸ CUL1 ▸ CEP78 ▸ PSEN1 ▸
PRKAA1 ▸ PRKAG2 ▸ CCNH ▸ SUB1 ▸ EPX ▸ GRB14 ▸ ARSA ▸
TNFRSF10A ▸ DST ▸ CEP63 ▸ CEP135 ▸ SETD2 ▸ CEP152 ▸ IRF5 ▸
CEP70 ▸ CTSL ▸ FOXO1 ▸ GRB7 ▸ WNT1 ▸ CEP76 ▸ MAP2K4 ▸
HSF1 ▸ VIM ▸ DERL1 ▸ CEP19 ▸ CEP112 ▸ MAP2K7 ▸ TCHP ▸
CEP290 ▸ IRF2 ▸ NPY6R ▸ EHMT1 ▸ CEP192 ▸ CEP44 ▸ ALK ▸
DES ▸ ATF5 ▸ SETBP1 ▸ HSP90AA1 ▸ TRAF3 ▸ GRB2 ▸ CEP57 ▸
SEC14L2 ▸ CEP55 ▸ MAP2K5 ▸ CD40 ▸ PRKAR1A ▸ LAT ▸ HIP1 ▸
PRKAB2 ▸ RAD17 ▸ VCP ▸ RASA1 ▸ CTNND1 ▸ TARDBP ▸ HIST2H2BE ▸
PSMD10 ▸ PTBP1 ▸ IGF1R ▸ CEP72 ▸ ELAVL1 ▸ BIRC8 ▸ MAP2K3 ▸
PLOD2 ▸ PRKAR2B ▸ MAP2K6 ▸ HUNK ▸ CEP89 ▸ CARD16 ▸ BACE1 ▸
CEP41 ▸ ATG5 ▸ IKBKG ▸ CEP120 ▸ CEP97 ▸ CEP350 ▸ LYPLA1 ▸
CEP95 ▸ MIF ▸ FUT1 ▸ CEP164 ▸ PIDD ▸ PRKAA2 ▸ CCR3 ▸
DNAJC5 ▸ HCLS1 ▸ FLT3 ▸ CCK ▸ MTA3 ▸ CD2 ▸ TRAF7 ▸
NANOG ▸ ACIN1 ▸ CCR8 ▸ RARA ▸ CDK6 ▸ DAPK2 ▸ PLD3 ▸
PRG2 ▸ CDK10 ▸ DAP3 ▸ PMEL ▸ TYR ▸ PC ▸ HTRA1 ▸
CDK7 ▸ SLPI ▸ PSMB9 ▸ MED8 ▸ HTRA4 ▸ S100A12 ▸ APOE ▸
MTX1 ▸ PAN3 ▸ CCR2 ▸ C22orf29 ▸ IRF7 ▸ GPI ▸ IL1RN ▸
MED14 ▸ IRF9 ▸ TSC22D3 ▸ STSP1 ▸ RAC3 ▸ IDO1 ▸ TAC3 ▸
LGALS1 ▸ NLRP7 ▸ NANOS2 ▸ GJA1 ▸ EIF4G1 ▸ SERP2 ▸ GNRH1 ▸
LRP1 ▸ MED25 ▸ MED23 ▸ EIF4G2 ▸ ADM ▸ THBS1 ▸ ATM ▸
APEX1 ▸ CAPNS1 ▸ DHCR24 ▸ PLD5 ▸ MED26 ▸ CDK13 ▸ CYR61 ▸
KLF4 ▸ SMAD3 ▸ ANXA6 ▸ NOTCH1 ▸ CHUK ▸ IFNA5 ▸ NUP210 ▸
NTF4 ▸ HMGCR ▸ GSTT1 ▸ ITCH ▸ MED4 ▸ BLM ▸ E2F3 ▸
HRD ▸ DAXX ▸ JAK1 ▸ TNFRSF8 ▸ ANP32A ▸ MED17 ▸ DYRK1A ▸
EMP1 ▸ ANGPT4 ▸ MED24 ▸ MT4 ▸ NUP43 ▸ COP ▸ SAA1 ▸
TRAF4 ▸ GYS1 ▸ NODAL ▸ EEF1A2 ▸ CDK9 ▸ IFIH1 ▸ CTNNBL1 ▸
GHSR ▸ NAIP ▸ SDS ▸ RAD1 ▸ TFAP2A ▸ NUAK1 ▸ PPT1 ▸
IRS1 ▸ MTA2 ▸ RAD52 ▸ CPA1 ▸ GRP ▸ MAP2 ▸ TGFB3 ▸
SHH ▸ TGM2 ▸ PXN ▸ APOBEC3D ▸ RAD21 ▸ MED13 ▸ PLK1 ▸
CALR ▸ CDK17 ▸ ODC1 ▸ NACA ▸ SREBF1 ▸ TET2 ▸ CDK14 ▸
SREBF2 ▸ ACR ▸ TET1 ▸ GNA11 ▸ PIN1 ▸ MAP3K7 ▸ FAF1 ▸
ETS1 ▸ NUP62 ▸ SERPINF1 ▸ CCNC ▸ TRA ▸ PDGFB ▸ CIB1 ▸
KMT2A ▸ MTA1 ▸ NR0B1 ▸ ID3 ▸ VIP ▸ HIPK2 ▸ MT3 ▸
GLI1 ▸ PGF ▸ RUNX3 ▸ RHO ▸ RAD18 ▸ GPX3 ▸ CSF1 ▸
MED21 ▸ TNFSF12 ▸ PTH ▸ GYS2 ▸ RAD50 ▸ MTOR ▸ TAC4 ▸
FAM168B ▸ CRYAB ▸ CTRL ▸ SIVA1 ▸ ADH5 ▸ ABCD1 ▸ TMED7 ▸
CALML3 ▸ SPP1 ▸ CISH ▸ CCR1 ▸ EMP2 ▸ IGFBP3 ▸ CCR10 ▸
RBL2 ▸ ACSM3 ▸ CDC42 ▸ CALB1 ▸ EMP3 ▸ CFL1 ▸ FHIT ▸
CDCA5 ▸ RIPK4 ▸ TAC1 ▸ VDAC3 ▸ SMAD4 ▸ CDK3 ▸ PLD6 ▸
PRG4 ▸ ING1 ▸ QRICH1 ▸ BNIP3 ▸ MED15 ▸ BCAP31 ▸ PARG ▸
PAWR ▸ MED12 ▸ NUP214 ▸ UCP2 ▸ HTRA3 ▸ WNT3A ▸ CENPK ▸
ETS2 ▸ TET3 ▸ CDK18 ▸ CDK20 ▸ JAK3 ▸ HDAC6 ▸ CDK15 ▸
PAN2 ▸ DLG1 ▸ BAG3 ▸ CCL19 ▸ MED7 ▸ PRG3 ▸ MST1R ▸
GPX1 ▸ AIP ▸ IRF8 ▸ CA8 ▸ PLD4 ▸ CDK12 ▸ PAEP ▸
STC1 ▸ CPOX ▸ MME ▸ SERPINA1 ▸ NAB1 ▸ CCR6 ▸ AFP ▸
PSENEN ▸ APIP ▸ CDK1 ▸ IAPP ▸ NPPA ▸ MED1 ▸ PTPN11 ▸
QRICH2 ▸ EIF4G3 ▸ SMAD7 ▸ CDK16 ▸ NLRP5 ▸ XAF1 ▸ DIDO1 ▸
TRAF5 ▸ EDNRA ▸ ACAD8 ▸ CCR5 ▸ CCR4 ▸ NLRC5 ▸ SERPINB9 ▸
CXCL13 ▸ CD8B ▸ FKBP4 ▸ MICE ▸ IFI44 ▸ RAC2 ▸ MED6 ▸
EML2 ▸ SEPT4 ▸ NTN1 ▸ NUP153 ▸ SATB1 ▸ HRK ▸ ANG ▸
VDAC2 ▸ SHC1 ▸ KLKB1 ▸ LRRC59 ▸ STX2 ▸ TNFRSF10B ▸ ATG3 ▸
E2F2 ▸ HDAC4 ▸ NAB2 ▸ XRCC6 ▸ ERVK-6 ▸ CCR9 ▸ CFTR ▸
KLK3 ▸ PTCH1 ▸ IFNA2 ▸ CDK19 ▸ IL1R1 ▸ PLEKHO1 ▸ RNF2 ▸
EIF3J ▸ KEAP1 ▸ PRF1 ▸ PTMA ▸ HEY2 ▸ BCAR1 ▸ MAP3K14 ▸
DSG2 ▸ SAV1 ▸ AR ▸ ELANE ▸ HNRNPU ▸ BIRC4 ▸ NFE2L2 ▸
PDE10A ▸ UBE4B ▸ HNRNPD ▸ LPAR1 ▸ FUS ▸ CDK11B ▸ ATN1 ▸
PPARGC1A ▸ CTTN ▸ SCAF11 ▸ PTGES3 ▸ MAP4K1 ▸ FBXW11 ▸ MLH1 ▸
DBNL ▸ DSG3 ▸ STK24 ▸ IQGAP1 ▸ YWHAE ▸ UNC5B ▸ ARHGDIB ▸
MEF2A ▸ ZBTB16 ▸ PIP5K1A ▸ NVL ▸ PLA2G4A ▸ PPP3CA ▸ NEO1 ▸
NGFRAP1 ▸ SDC2 ▸ PSIP1 ▸ UBC ▸ MDC1 ▸ IL1R2 ▸ THAP11 ▸
NUCB2 ▸ NDUFS1 ▸ FUK ▸ NUMA1 ▸ GAS2 ▸ ACTA1 ▸ SOCS5 ▸
GZMM ▸ PDE5A ▸ NFATC2 ▸ HRAS ▸ NGFR ▸ GORASP1 ▸ PICALM ▸
TRIM28 ▸ LPAR3 ▸ NR3C1 ▸ AIFM1 ▸ AKAP8 ▸ CDC2L1 ▸ CDK11A ▸
GRIPAP1 ▸ ARHGDIA ▸ PLA2G4B ▸ GMNN ▸ RBX1 ▸ TP73 ▸ EIF4A1 ▸
CAD ▸ KARS ▸ DSG1 ▸ EIF3S10 ▸ TNS4 ▸ CDC2L2 ▸ EIF4B ▸
YWHAG ▸ MAPK8IP3 ▸ SYF2 ▸ ACVR1C ▸ NMT2 ▸ CD247 ▸ HNRNPA0 ▸
SARS2 ▸ ATG4D ▸ IFT57 ▸ DCTN1 ▸ RABEP1 ▸ WNK3 ▸ COPS6 ▸
TNFRSF25 ▸ MAPT ▸ BMX ▸
Data information
Please see the Gene Interactions Track Manual.