Gene interactions and pathways from curated databases and text-mining

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IL2 — UGCG

Text-mined interactions from Literome

Wu et al., Eur J Immunol 1991 : The suppression is observed at the protein and at the mRNA levels and it is not secondary to the GCS induced inhibition of IL2 production
Hasan et al., Age (Dordrecht, Netherlands) 2012 : GCs also inhibit interleukin-2 synthesis through suppressing T cell receptor signal that leads to loss of T cell activation, proliferation, and B-cell activation
Krouwels et al., Am J Respir Cell Mol Biol 1996 : Interestingly, two categories of clones were distinguished based on the effects of GCS on IL-2 production and IL-2R alpha expression and proliferation ; 1 ) In low IL-2 producers DEX blocked IL-2 production and decreased IL-2R alpha expression and proliferation ; 2 ) In high IL-2 producers DEX inhibited IL-2 production partially and enhanced IL-2R alpha expression and proliferation