Gene interactions and pathways from curated databases and text-mining

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INS — RHOA

Text-mined interactions from Literome

Sandu et al., J Appl Physiol 2001 (Hypertension) : Furthermore, expression of a dominant negative RhoA decreased basal as well as thrombin induced MBS ( Thr695 ) phosphorylation and caused insulin activation of MBP
Lee et al., J Cell Physiol 2009 : These data indicate that RhoA/Rok is involved in substratum mediated regulation of insulin signaling in MECs, and under the conditions where proper adhesion to BM is missing, such as after wounding and during mammary gland involution, insulin mediated cellular differentiation and survival would be defective