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JUN — MSK32

Text-mined interactions from Literome

Gesser et al., Inflamm Res 2011 (Psoriasis) : Dimethylfumarate inhibits MIF induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun ( S63 ) and p-p53 ( S15 ) expression ... Our results indicate that the specific inhibitory effects of DMF on RSK1 and MSK1 activation together with the induction of p-c-Jun ( S63 ) and p-p53 ( S15 ) lead to the inhibition of keratinocyte proliferation, partly explaining the anti-psoriatic effect of DMF
Li et al., BMC cancer 2013 (Cell Transformation, Viral...) : Using MSK1 inhibitor H89 or siRNA-MSK1, the regulatory role of MSK1 on histone H3 phosphorylation and AP-1 activation were analyzed