Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Chemtob et al., Dev Pharmacol Ther 1990 : PGF2 alpha ( 0.01 micrograms/kg, n = 8 ), which is a potent cerebral vasoconstrictor in adults, and PGI2 ( 0.1 micrograms/kg, n = 6 ) significantly increased CBF in newborn piglets ( p less than 0.05 )
Aranda et al., J Lipid Mediat 1993 (Hypertension...) : PGI2 also increased CBF by 27 % ( p < 0.01 )
Zhao et al., Cardiovasc Res 1996 : PGI2 ( 1.0 microgram/kg ) increased CBF by 55 +/- 15 % from 33 +/- 5.3 ml/min and decreased LDCR by 42 +/- 9 % ( both P < 0.05, compared with before NLA ) from 3.29 +/- 0.39 mmHg/ml/min. Infusion of L-arginine ( 100 mg/kg ) reversed the action of NLA. For example, PGI2 ( 1.0 microgram/kg ) increased CBF by 115 +/- 15 % from 36 +/- 6 ml/min and decreased LDCR by 68 +/- 3 % from 3.02 +/- 0.36 mmHg/ml/min ( both P > 0.05, compared with before NLA )