Yu et al., Biochem Pharmacol 2006
(Disease Models, Animal...) :
In the present study, we investigated whether the activation of Jak/Stat signaling mediates IL-1beta expression in pancreatic acinar AR42J cells stimulated with cerulein in vitro as well as the rats with cerulein pancreatitis in vivo using AG490, the Jak2 inhibitor
Kanda et al., Endocrinology 2008
:
IL-1beta induced serine phosphorylation of inhibitory kappaBalpha, STAT1 , and STAT3
Honsho et al., Circ Res 2009
(Endomyocardial Fibrosis...) :
Promoter analysis showed that stretch mediated IL-1beta activates JAK/STAT to transcriptionally regulate the IGF-1 gene