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NFKB1 — ROCK1

Text-mined interactions from Literome

Wei et al., Mol Pharmacol 2006 : Further studies showed that LPS down-regulated Rho and ROCK activity, whereas IL-1beta increased them, suggesting a negative role of Rho and ROCK signaling, which is regulated in contrary manners by IL-1beta and LPS, in IKK/NF-kappaB activation
Rodriguez et al., Cell Signal 2007 : ROCK I-mediated activation of NF-kappaB by RhoB ... Activation of NF-kappaB by RhoB is dependent upon ROCK I but not PRK I ... Thus, ROCK I cooperates with RhoB to activate NF-kappaB, and suppression of ROCK I activity by genetic or pharmacological inhibitors blocks NF-kappaB activation ... Thus, ROCK I cooperates with RhoB to activate NF-kappaB, and suppression of ROCK I activity by genetic or pharmacological inhibitors blocks NF-kappaB activation
Shimada et al., FEBS Lett 2010 : In summary, MCP-1 production was partly regulated by ROCK acting upstream of p38 and JNK and mediated downstream by NF-kappaB