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HNRNPH1 — IL2
Text-mined interactions from Literome
Manome et al., Immunology 1999
(Dermatitis, Contact) :
Finally, we examined the effects of these chemicals on CD86 expression by three different macrophage subsets and
DCs induced from the cultures of human peripheral blood monocytes in the
presence of macrophage colony stimulating factor ( M-CSF ), M-CSF
+ interleukin-4 (IL-4), granulocyte-macrophage colony stimulating factor ( GM-CSF ), and GM-CSF + IL-4, respectively
Cassell et al., Scand J Immunol 2001
:
Single-cell and limiting dilution analyses indicate that individual T cells from normal and CD28-/- mice produce equivalent
interleukin (IL)-2 in
response to
DCs
Schnurr et al., Cancer Res 2001
(Pancreatic Neoplasms) :
Autologous mononuclear cells were cocultured with
DCs in the
presence of low-dose
interleukin (IL)-2 and IL-7 and were restimulated weekly with new DCs
Fikri et al., Scand J Immunol 2002
:
DCs were more efficient than monocytes in inducing gammadelta T-cell proliferation, and this response was
dependent on exogenous
IL-2 in both presentation modes
Sorg et al., J Immunother 2003
(Neoplasm Metastasis) :
Mature
DCs effectively clustered with naive T cells and potently
induced allogeneic T-cell proliferation and
IL-2 and IFNgamma but not IL-4 production
Ferreira et al., Scand J Immunol 2003
(Paracoccidioidomycosis) :
It was seen that
DCs from resistant mice
stimulated predominantly
interleukin-2 (IL-2) and interferon-gamma (IFN-gamma), whereas macrophages activated IL-10, IL-4 and IFN-gamma secreting T cells and B cells IL-4 and IL-10 only
Liu et al., Chin J Cancer 2003
(Breast Neoplasms) :
DCs were
stimulated by granulocyte/macrophage colony stimulating factor ( GM-CSF ),
interleukin-4(IL-4) , and tumor antigen
Feau et al., Blood 2005
:
In particular, we could show that
DCs from IL-15-deficient mice were strongly
impaired in the ability to produce
IL-2 after interactions with different microbial stimuli
Van Gulck et al., Blood 2006
(HIV Seropositivity) :
Moreover, a significant
interleukin-2 (IL-2) T-cell response was
induced by
DCs electroporated with hHxB-2 or proviral gag mRNA
Yamazaki et al., Proc Natl Acad Sci U S A 2006
(Graft vs Host Disease) :
Likewise,
DCs and not spleen cells were effective in sustaining expression of the transcription factor Foxp3 in Tregs, but neither
IL-2 nor CD80/86 was
required for this effect in the cultures
Hua et al., Nan Fang Yi Ke Da Xue Xue Bao 2006
:
The
DCs were derived from healthy human peripheral blood monocytes in the
presence of granulocyte-macrophage colony stimulating factor,
interleukin (IL)-4 and tumor necrosis factor (TNF) alpha
Salazar et al., Eur Cytokine Netw 2007
:
An assay for antigen presenting capacity demonstrated that
4hLPS/DCs induced secretion of
IL-2 from an OTH4 T cell hybridoma, indicating a functional presenting activity
Fan et al., Clinical and vaccine immunology : CVI 2007
(HIV Infections...) :
The ability of
DCs from HCV infected persons to stimulate allogeneic CD4+ T cells or
induce IL-2 , IL-5, or IL-10 in a mixed lymphocyte reaction was not impaired
Sá-Nunes et al., J Immunol 2007
:
In addition, saliva significantly suppressed the ability of
DCs to
stimulate Ag-specific CD4 ( + ) T cell proliferation and
IL-2 production
Yamazaki et al., Blood 2007
:
The required
IL-2 was
induced by
DCs that expressed CD80/CD86 costimulatory molecules
Hegde et al., J Leukoc Biol 2008
:
Also, CD44-deficient
DCs induced significantly decreased proliferation as well as
IL-2 and IFN-gamma production from allogeneic T cells
Wang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2008
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
PD-L1 blockaded
DCs could enhance T lymphocyte proliferation,
increase the secretion of
IL-2 and IFN-gamma, and inhibit the production of IL-10
Liu et al., Infect Immun 2009
:
In model antigen presentation experiments,
DCs from lpg2 ( - ) mutant infected mice
induced more gamma interferon ( IFN-gamma ) and
IL-2 production by Leishmania-specific T cells than those from WT-infected mice
Walch et al., J Immunol 2009
:
DCs infected with HSV-1 showed enhanced surface expression of the costimulatory molecule CD252 ( CD134L ) compared with Listeria infected DC and
induced enhanced secretion of
IL-2
Zhu et al., J Interferon Cytokine Res 2009
:
DCs treated with HMGB1 ( 1 microg/mL for 48 h ) promoted T-cell proliferation as well as differentiation, and markedly
up-regulated IL-2 , IL-2R expression and intranuclear NF-kappaB activation
Tao et al., Hum Gene Ther 2010
:
These findings suggest that rMVA encoding survivin and
IL-2 can effectively
stimulate the activation of human
DCs and overcome defects such as impairment of DC maturation and apoptosis of lymphocytes that are caused by vector alone
Laabs et al., Clinical and vaccine immunology : CVI 2009
:
Here we report that the Lm/CpG vaccine
induced dermal
DCs , but not bone marrow derived DCs, to produce
interleukin-2 (IL-2)
Slámová et al., Parasite Immunol 2011
:
The ability of Borrelia exposed
DCs to
induce both proliferation and
IL-2 production by specific CD4+ T cells was significantly reduced by tick saliva
Kim et al., Clin Exp Immunol 2012
(Carcinoma, Renal Cell...) :
Interaction of
DCs pulsed with CA9-AbOmpA fusion proteins with naive T cells
stimulated secretion of
IL-2 , interferon ( IFN ) -? and tumour necrosis factor (TNF)-a in T cells
Byun et al., Biochem Biophys Res Commun 2012
(Inflammation) :
In addition, EGCG treated
DCs inhibited lipopolysaccharide (LPS) induced production of pro-inflammatory cytokines ( tumor necrosis factor [TNF ] -a,
interleukin [ IL]-1ß, and IL-6 ) and activation of mitogen activated protein kinases ( MAPKs ), e.g., extracellular signal regulated kinase 1/2 ( ERK1/2 ), p38, c-Jun N-terminal kinase (JNK), and nuclear factor ?B ( NF-?B ) p65 translocation through 67LR
Byun et al., J Biol Chem 2012
:
We further found that MAP CobT treated
DCs activated naive T cells, effectively polarized CD4 ( + ) and CD8 ( + ) T cells to secrete IFN-? and
IL-2 , but not IL-4 and IL-10, and induced T cell proliferation
Xie et al., J Surg Res 2013
:
In addition, RelB
shRNAi-DCs resulted in the reduced secretion of
IL-2 and interferon-? and increased levels of IL-10 and IL-4
Khanna et al., Transplantation 1998
:
In addition, however, a link was observed between the beneficial effect of donor BM and comparatively large numbers of donor major histocompatibility complex class II ( IAb+ ) -positive cells in recipients ' spleens, and in cultures of granulocyte-macrophage colony stimulating factor
+ interleukin-4 stimulated
DCs from recipients ' BM