Stinson et al., Science signaling 2011
(Breast Neoplasms...) :
The basal-like transcription factor FOSL1 ( also known as Fra-1 ) directly stimulated the transcription of miR-221/222 , and the abundance of these miRNAs decreased with inhibition of MEK ( mitogen activated or extracellular signal regulated protein kinase kinase ), placing miR-221/222 downstream of the RAS pathway
Horita et al., Arterioscler Thromb Vasc Biol 2011
:
Increased miR-21 expression was dependent on induction of Fos related antigen (FRA)-1 , which is a direct target of miR-143 ... Introducing miR-143 into SRF depleted SMCs reduced FRA-1 expression and miR-21 levels and restored PTEN expression