◀ Back to IFNG

GAST — IFNG

Text-mined interactions from Literome

Bauvois et al., Oncogene 2000 (Leukemia, B-Cell) : As shown by electrophoretic mobility shift assay, RA and IFN-gamma increased the binding of a nuclear protein to the GAS-CD26 element
Hua et al., J Neurochem 2002 : Electrophoretic mobility shift analysis ( EMSA ) demonstrated that IFN-gamma induced sustained IFN-gamma activated sequence ( GAS ) binding, while IFN-beta induced transient GAS binding ... When used together, IFN-beta inhibited IFN-gamma induced GAS binding activity
Miller et al., J Interferon Cytokine Res 2004 : Core expression resulted in dose dependent activation of the ISRE and gamma activated sequence (GAS) promoters, in both the absence and the presence of either IFN-alpha or IFN-gamma
Ji et al., Glia 2004 (Encephalitis) : Since interferon-gamma (IFN-gamma) induced GAS-luciferase activity and tyrosine phosphorylation of STAT1 and STAT3 were lower in CIS transfected cells compared to control vector transfected cells, CIS could have anti-inflammatory activity
Zavros et al., Oncogene 2005 (Adenocarcinoma...) : IFNgamma significantly stimulated phosphorylation of STAT3 in the MKN45 cell line, but not gastrin
Kaneko et al., Exp Dermatol 2006 : Transient transfection studies with BPAG1 promoter-reporter gene constructs containing mutated IGIE ( with TT to GG transversions in the region of 5'ISRE, GAS, and 3'ISRE ) demonstrated that disruption of the ISRE sequences, but not GAS , markedly suppressed the BPAG1 basal promoter activity and resulted in attenuated IFNgamma response in keratinocytes
Hatziieremia et al., Br J Pharmacol 2006 (Inflammation) : It also inhibited IFNgamma stimulated iNOS induction and GAS/GAF-DNA binding
Vadrot et al., J Interferon Cytokine Res 2006 (Carcinoma, Hepatocellular) : We studied ( 1 ) IFN-gamma induced apoptosis, ( 2 ) protein expression of Stat1, ( 3 ) binding of nuclear proteins to IFN-gamma activated sequence ( GAS ) , ( 4 ) mRNA and expression of proteins acting in apoptosis, and ( 5 ) HuH7 sensitivity after inducible nitric oxide synthase (iNOS) siRNA transfection
Mirkovitch et al., Mol Cell Biol 1992 : These results demonstrate the involvement of the GAS in IFN-alpha and -gamma induction of GBP and suggest the presence of an altered DNA conformation or a small protein in the major groove of the GAS associated with ongoing GBP transcription
Kasper et al., J Interferon Cytokine Res 2007 : EMSA showed that GM-CSF inhibited IFN-alpha induced and IFN-gamma induced IFN-gamma activator sequence ( GAS ) binding activity
Abdalla et al., Iran J Immunol 2008 : Gastrin , secretin, GIP and VIP increased IL-2 and IFN- gamma levels under some culture conditions and depressed IL-2 under other conditions
Rein et al., Nucleic Acids Res 1994 : Our data confirm the crucial role of GAS in transcriptional activation by IFN gamma and are consistent with induced binding of p91 to GAS
Eilers et al., Immunobiology 1995 (Lymphoma, Large B-Cell, Diffuse) : Monocytic differentiation led to an increased transcriptional response of GAS containing genes to IFN-gamma
Lindner et al., Mol Cell Biochem 1997 (Breast Neoplasms) : Similarly, transcriptional induction of chimeric reporter plasmids driven by an IFN-gamma inducible promoter ( GAS ; IFN-gamma activated site ) was also enhanced by the combination of IFN-gamma and tamoxifen
Agresti et al., Eur J Neurosci 1998 : The existence of a synergism between IFN-gamma and TNF-alpha in stimulating IRF-1 expression at the transcriptional level was supported by IRF-1 promoter analysis : IFN-gamma directly induced the binding of STAT-1 homodimers to the GAS element, while NF-kappaB binding to the kappaB sequence was activated by TNF-alpha only after IFN-gamma treatment
Min et al., Circ Res 1998 : In ECs, however, IFN-gamma and IFN-alpha/beta act through both the GAS and ISRE