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CEBPB — IFNG

Text-mined interactions from Literome

Roy et al., J Biol Chem 2000 : Interestingly, the expression of C/EBP-beta , not the other members of its family, is induced by IFN-gamma
Gupta et al., Kidney Int 2000 : To test the hypothesis that alpha-MSH inhibits the expression of inducible trans activating factors involved in NOS2 regulation, we used RAW 264.7 macrophage cells to examine the effects of alpha-MSH on the activation of nuclear factor-kappaB (NF-kappaB) and CCAAT/enhancer binding protein-beta ( C/EBPbeta ), trans acting factors known to be involved in LPS + interferon (IFN)-gamma induction of the NOS2 gene
Berberich-Siebelt et al., Eur J Immunol 2000 : C/EBPbeta enhances IL-4 but impairs IL-2 and IFN-gamma induction in T cells ... Retroviral overexpression of C/EBPbeta in murine EL-4 thymoma cells led to a strong induction of endogenous IL-4 and a reduction in IL-2 and IFN-gamma expression
Jana et al., J Biol Chem 2001 : Stimulation of IFN-gamma mediated activation of NF-kappaB but not of C/EBPbeta by CD40 ligation suggests that CD40 ligation stimulates the expression of iNOS in IFN-gamma treated BV-2 microglial cells through the stimulation of NF-kappaB activation
Salmenperä et al., Am J Physiol Cell Physiol 2003 : Interferon-gamma induces C/EBP beta expression and activity through MEK/ERK and p38 in T84 colon epithelial cells ... We investigated the role of IFN-gamma and MAPKs on the expression and activity of the transcription factor CCAAT/enhancer binding protein-beta ( C/EBP beta ) in the T84 colon epithelial cell line ... IFN-gamma induced the expression and activity of C/EBP beta and subsequently increased the secretion of IL-6 from these cells ... Treatment with the p38 inhibitor SB-203580, the MEK1 and MEK2 inhibitor U-0126, or the translational inhibitor cycloheximide inhibited the induction of C/EBP beta and IL-6 by IFN-gamma , whereas the MEK1 inhibitor PD-98059 or the tyrosine kinase inhibitor genistein had no effect ... These results suggest a role for MEK2 and p38 in IFN-gamma mediated signal transduction and induction of C/EBP beta expression and activity associated with interleukin-6 (IL-6) secretion in colon epithelial cells
Iacobelli-Martinez et al., J Virol 2005 (Adenoviridae Infections) : Analysis of transcription factor activity required for cytokine expression indicated that CD46 utilizing Ads preferentially inhibited IFN-gamma induced C/EBPbeta protein expression, consequently reducing its ability to form DNA complexes
Ghosh et al., J Cell Physiol 2006 : The results demonstrated that IFN-gamma caused increased C/EBPbeta expression in dermal fibroblasts and enhanced its binding to cognate DNA sequences in the alpha2 ( I ) procollagen gene ( COL1A2 ) promoter in vitro and in vivo ... Disruption of C/EBP binding by deletion or site directed mutagenesis abrogated the inhibition of collagen promoter activity in transient transfection assays, as did cotransfection with dominant negative C/EBPbeta, indicating a functional role of cellular C/EBPbeta in mediating the IFN-gamma response
Cieslik et al., Mol Pharmacol 2006 : We have reported previously that salicylate at 10 ( -5 ) M inhibited LPS/IFNgamma induced CCAAT/enhancer binding protein beta ( C/EBPbeta ) binding at 4 h but not at 8 or 24 h
Deng et al., Arterioscler Thromb Vasc Biol 2007 : IFNgamma blocked C-Jun and C/EBPbeta but not C-Fos or p50 NF-kappaB binding as determined by in vitro binding assays and chromatin immunoprecipitation assay
Gade et al., Mol Cell Biol 2008 (MAP Kinase Signaling System) : C/EBP-beta binds to this site in an IFN-gamma dependent manner
Xu et al., Stem Cells 2009 : We further found that, while either IFNgamma or TNFalpha alone induced minor expression of C/EBPbeta in MSCs, this transcription factor was dramatically upregulated when these cytokines were added together ... Furthermore, while STAT1 is critical in IFNgamma signaling, we found that STAT1 knockdown in MSCs did not affect C/EBPbeta expression or the synergistic induction of IL-6 and CXCL1 by IFNgamma and TNFalpha
Kalvakolanu et al., Autophagy 2012 (Bacterial Infections) : IFNG stimulated proteolytic cleavage of ATF6, and MAPK1/3 ( ERK2/1 ) -dependent phosphorylation of CEBPB together control the expression of Dapk1