Gene interactions and pathways from curated databases and text-mining

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EPHB2 — LSP1

Text-mined interactions from Literome

Cao et al., J Biol Chem 2001 : Expression of constitutively active PKCbetaI protein in W10 cells activates the mitogen activated protein kinase ERK2, whereas expression of B-LSP1 inhibits anti-IgM induced activation of ERK2 , suggesting that anti-IgM activated PKCbetaI is involved in the activation of ERK2 and that inhibition of ERK2 activation contributes to the increased anti-IgM induced apoptosis
Harrison et al., J Cell Sci 2004 (Lymphoma, B-Cell...) : To understand the role of LSP1 in the regulation of PKCbetaI dependent ERK2 activation, we investigated whether LSP1 interacts with ERK/MAP kinase pathway components and targets these proteins to the actin cytoskeleton