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IBD5 — PTGS2

Text-mined interactions from Literome

Guo et al., Eur J Pharmacol 2001 (Colitis...) : The present study suggests that the highly induced cyclooxygenase-2 expression not only plays a pathogenic role in 2,4,6-trinitrobenzenesulfonic acid induced inflammatory bowel disease , but also contributes to the adverse action of cigarette-smoke exposure on this disorder
Cipolla et al., Pharmacol Res 2002 (Inflammatory Bowel Diseases) : If COX-2 inhibition plays a key role in suppressing the inflammatory process, recent evidence suggests that COX-2 products are involved in maintaining the integrity of intestinal mucosa, in the healing of gastrointestinal ulcers and in the modulation of inflammatory bowel disease ( IBD )
Berg et al., Gastroenterology 2002 (Colitis...) : COX-1- or COX-2-selective inhibitors used alone did not induce IBD in IL-10 ( -/- ) mice
Hendel et al., Am J Gastroenterol 1997 (Acute Disease...) : The purpose of this study was to evaluate the role of COX-2 in inflammatory bowel disease