Gene interactions and pathways from curated databases and text-mining

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GSR — IRF6

Text-mined interactions from Literome

Motegi et al., J Leukoc Biol 2008 (Bacterial Infections...) : We previously proposed that mouse CD8 ( + ) CD122 ( + ) T cells and human CD57 ( + ) T cells, which increase with age and exhibit potent IFN-gamma production, represent a double edged sword as they play critical roles in host defense and the lethal IL-12/LPS induced generalized Shwartzman reaction (GSR)
Iszard et al., Toxicology 1995 : Cd significantly increased, whereas LPS reduced , the activities of selenium dependent glutathione peroxidase and glutathione reductase