Gene interactions and pathways from curated databases and text-mining

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NM — TLR4

Text-mined interactions from Literome

Fan et al., Nat Med 2003 : Toll-like receptor-4 (TLR4) signaling augments chemokine induced neutrophil migration by modulating cell surface expression of chemokine receptors
Alves-Filho et al., Crit Care Med 2006 (Sepsis) : In the present study, we investigated whether TLR4 is involved in the failure of neutrophil migration in mice subjected to polymicrobial or Gram negative sepsis
Alves-Filho et al., Endocr Metab Immune Disord Drug Targets 2006 (Sepsis) : It seems that the failure of neutrophil migration is dependent on toll-like receptor 4 (TLR4) and mediated by cytokines and chemokines, which induce the production of nitric oxide that inhibits neutrophil adhesion to venular endothelium and also the neutrophil chemotactic ability