Giehl et al., Oncogene 2000
(Pancreatic Neoplasms) :
Stimulation of cells with epidermal growth factor (EGF) or fetal calf serum ( FCS ) resulted in activation of N-Ras , but not K-Ras, as well as activation of c-Raf, MEK-1, and p42 MAPK Whitwam et al., Oncogene 2007
(Cell Transformation, Neoplastic...) :
Although both NRAS and KRAS activate mitogen activated protein kinase signaling, only NRAS enhances MYC activity in these cells
Hamilton et al., Oncogene 1998
:
Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo