Chen et al., Mol Pharmacol 2000
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However, neither the mitogen activated protein kinase kinase inhibitor PD 98059 nor the p38 inhibitor SB 203580 affected IL-1beta induced ICAM-1 expression
Wang et al., J Immunol 2001
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ICAM-1 cross linking induced phosphorylation of the p38 mitogen activated protein kinase ( MAPK ) that was inhibited by allopurinol and also induced an increase in the activity of the p38 MAPK that was inhibited by SB203580
Jijon et al., Am J Physiol Cell Physiol 2002
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In this study we examined the roles of extracellular signal regulated kinase ( ERK ) and p38 in the expression of interleukin-8 (IL-8) and intercellular adhesion molecule-1 ( ICAM-1 ) using the human intestinal cell line HT-29
Wang et al., J Immunol 2006
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ICAM-1 engagement by HRV and cross linking Abs also induced phosphorylation of p38 in a Syk dependent manner, and conversely, knockdown of Syk by short interfering ( si ) RNA substantially diminished p38 activation and IL-8 gene expression