Gene interactions and pathways from curated databases and text-mining

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EPHB2 — TGM5

Text-mined interactions from Literome

Singh et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Further, by using stable SH-SY5Y cell lines ( overexpressing wild-type, C277S mutant, and antisense TGase ), we demonstrate that transglutaminase activity is required for activation of RhoA, ERK1/2 , JNK1, and p38gamma MAP kinases
Garcia et al., Biochem J 2010 (MAP Kinase Signaling System) : We also show that Gq plus Gi- or Gi plus Gz-mediated platelet aggregation, ERK phosphorylation and thromboxane A2 generation in human platelets was inhibited by TGX-221 , a PI3Kbeta-selective inhibitor, but not by PIK75 ( a PI3Kalpha inhibitor ), AS252424 ( a PI3Kgamma inhibitor ) or IC87114 ( a PI3Kdelta inhibitor )