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NUP43 — PTGS2

Text-mined interactions from Literome

Goppelt-Struebe et al., Biochem J 1999 : Independent regulation of cyclo-oxygenase 2 expression by p42/44 mitogen activated protein kinases and Ca2+/calmodulin dependent kinase
Ohnaka et al., Hypertension 2000 : PD98059 and SB203580 markedly enhanced the decay of COX-2 mRNA induced by Ang II, implying that p42/44 and p38 MAPK activated by Ang II play a role in the regulation of COX-2 through stabilization of its mRNA
Chen et al., Mol Pharmacol 2001 : The role of p44/42 mitogen activated protein kinase ( MAPK ), p38, and c-Jun NH ( 2 ) -terminal kinase ( JNK ) in tumor necrosis factor (TNF)-alpha induced cyclooxygenase (COX)-2 expression was studied in NCI-H292 epithelial cells
Fernández et al., Eur J Immunol 2002 : All of these stimuli were capable of activating the cells ; however, different patterns of response were observed as regards activation of the p42-MAP/ERK kinase, triggering of the NF-kappaB/Rel system, production of chemotactic cytokines, and induction of the expression of cyclooxygenase-2 (COX-2)
Hahn et al., Biochem J 2002 : An intact cytoskeleton, however, was not required for p42/44 MAP-kinase activation or Cox-2 induction , as shown by the actin depolymerizing agent cytochalasin D. Toxin B did not influence functionality of LPA receptors, because G ( i ) -mediated Ca ( 2+ ) release from intracellular stores remained unchanged
Luo et al., Cell Signal 2003 : Induction of cyclooxygenase-2 by lipopolysaccharide in canine tracheal smooth muscle cells : involvement of p42/p44 and p38 mitogen activated protein kinases and nuclear factor-kappaB pathways
Gardner et al., FASEB J 2003 (Lung Neoplasms) : Furthermore, the p38/MAPK inhibitor, SB203528, and the p42/44 inhibitor, PD98059, blocked methanandamide mediated induction of PGE2 and COX-2
Lin et al., Cell Signal 2004 : Tumor necrosis factor-alpha induced cyclooxygenase-2 expression in human tracheal smooth muscle cells : involvement of p42/p44 and p38 mitogen activated protein kinases and nuclear factor-kappaB
Lin et al., J Biomed Sci 2004 : Induction of cyclooxygenase-2 expression in human tracheal smooth muscle cells by interleukin-1beta : involvement of p42/p44 and p38 mitogen activated protein kinases and nuclear factor-kappaB
Rodriguez et al., Am J Physiol Heart Circ Physiol 2006 : In addition, we conclude that the activation of mitogen activated protein kinases p42/p44 , protein kinase C, and nitric oxide synthase is necessary for the increase in COX-2 levels induced by BK because either of the specific inhibitors for these enzymes blocked the effect of BK. Using a similar approach, we further demonstrated that reactive oxygen species and cAMP were not mediators on this pathway
Lin et al., Cardiovasc Res 2009 : Our results suggest that in VSMCs, activation of p42/p44 MAPK, p38 MAPK, and NF-kappaB is essential for ATPgammaS induced COX-2 expression and PGE2 synthesis
Zhao et al., Mol Cell Biochem 2012 (MAP Kinase Signaling System) : Those that received PDGF-BB stimulation showed enhanced cyclooxygenase-2 (COX-2) expression and activation of phosphor-mitogen activated protein kinase ( MAPK ) p44/p42