Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
IRS1
→
AKT1S1
(increases, AKT1S1 Activity, IRS1 Activity)
Vander Haar et al., Nat Cell Biol 2007 Evidence: PRAS40 silencing inactivates insulin-receptor substrate-1 (IRS-1) and Akt, and uncouples the response of mTOR to Akt signals.