Gene interactions and pathways from curated databases and text-mining

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IFNA2 — IRF7

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Rubinstein et al., Antiviral Res 2000 : While interferon alpha A was more sensitive than interferon tau to the inhibitory effects of the IRF-2 DBD, IRF mediated gene induction is involved in successful interferon alpha and tau induced anti-VSV activity
Barnes et al., J Biol Chem 2001 : Virus-specific activation of a novel interferon regulatory factor , IRF-5, results in the induction of distinct interferon alpha genes
Zhu et al., Proc Natl Acad Sci U S A 2002 : By blocking the phosphorylation and nuclear translocation of IRF-7 , ORF45 efficiently inhibits the activation of interferon alpha and beta genes during viral infection
Hochhaus et al., Leukemia 1997 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Expression of interferon regulatory factor ( IRF ) genes and response to interferon-alpha in chronic myeloid leukaemia