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EGF — VDR

Text-mined interactions from Literome

Bareis et al., Exp Cell Res 2002 (Carcinoma...) : In the present study we addressed the question of whether the effects of epidermal growth factor (EGF) and of 1,25-D3 on VDR , CYP27B1, and CYP24 gene expression in human colon carcinoma cell lines also depend on the degree of cellular differentiation ... From the observed clonal differences in the regulatory effects of EGF and 1,25-D3 on VDR and CYP27B1 gene expression we suggest that VDR mediated growth inhibition by 1,25-D3 would be efficient only in highly differentiated carcinomas even when under mitogenic stimulation by EGF
Bruns et al., Endocrinology 1989 : EGF effects on calbindin-D9k and VDR were specific for the intestine, as EGF did not change kidney calbindin-D9k or kidney VDR