Gene interactions and pathways from curated databases and text-mining

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EGF — LRIG1

Text-mined interactions from Literome

Jensen et al., Proc Natl Acad Sci U S A 2006 : Down-regulation of Lrig1 using siRNA increased cell-surface EGF receptor levels, enhanced activation of downstream pathways, and stimulated proliferation
Stutz et al., Oncogene 2008 (Glioblastoma) : LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII