◀ Back to PPARG

CEBPD — PPARG

Text-mined interactions from Literome

Hamm et al., Ann N Y Acad Sci 1999 : Induction of PPAR gamma gene transcription during the differentiation of preadipocytes into adipocytes in vitro occurs following an initial phase of cell proliferation and requires a direct involvement of C/EBP beta, C/EBP delta , and glucocorticoids
Elberg et al., J Biol Chem 2000 : We demonstrate here that C/EBPalpha and C/EBPdelta , but not C/EBPbeta, induce the activity of the PPARgamma2 promoter in transiently transfected 3T3-L1 preadipocytes and bind to two juxtaposed low affinity C/EBP binding sites
Takata et al., J Biol Chem 2001 : PPARgamma activators also suppressed IL-1beta induced C/EBPdelta expression ... From these results, we conclude that the inhibitory effect of PPARgamma activators on PDGFalphaR expression is mainly mediated by C/EBPdelta suppression ... Regulation of C/EBPdelta by PPARgamma activators probably plays critical roles in modulating inflammatory responses in the arterial wall
Kurebayashi et al., Endocr J 2001 : Induction of C/EBPalpha and PPARgamma , which regulate the expression of many adipocyte related genes, is dependent on the expression of C/EBPbeta and C/EBPdelta at the early phase of adipocyte differentiation ... In fully differentiated adipocytes, TNF-alpha rapidly induced C/EBPbeta and C/EBPdelta , whereas it downregulated the expression of C/EBPalpha and PPARgamma
Takata et al., Circ Res 2002 (Inflammation) : In the present study, we showed that a high level of C/EBP-delta expression induced by inflammation positively regulated transcription and protein expression of PPAR-gamma in vascular smooth muscle cells ( VSMCs )
Lai et al., Biochim Biophys Acta 2008 : Overexpression of CEBPdelta (CEBPD) enhances lipid accumulation and specifically activates PPARG2 transcription in HepG2 cells ... By using 5'-serial deletion reporter analysis, we show that the region comprising the -457 to +129 base pairs is required for CEBPD response of the PPARG2 promoter ... Taken together, we suggest that suCEBPD/HDAC1/HDAC3 complex inactivates PPARG2 transcription, and the induction of CEBPD expression transiently activates PPARG2 transcription which is involved in adipocyte-like lipogenesis in HepG2 cells
Lee et al., Obesity (Silver Spring) 2009 : However, the mRNA levels of C/EBP-beta and -delta , the upstream regulators of PPAR-gamma and C/EBP-alpha, were not reduced by isorhamnetin
Choi et al., Life Sci 2009 : In the early stage of adipogenesis, magnolol induced gene expression of C/EBPdelta , C/EBPalpha and PPARgamma2 and during adipocyte differentiation, it also induced the expression of PPARgamma target genes such as aP2, LPL and adiponectin