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ACO2 — PPARA
Text-mined interactions from Literome
Lazennec et al., Mol Endocrinol 2000
:
Moreover, comparing PPAR alpha knockout ( KO ) with PPAR alpha WT mice, we show that the expression of the
acyl CoA oxidase ( ACO ) gene can be
regulated by PKA activated
PPAR alpha in liver
Bretillon et al., Lipids 2003
(Body Weight) :
In the present work, CFAM ( 0.5 % of the diet ) were administered for 3 wk to wild-type and PPARalpha-null mice of both genders to elucidate the
role of
PPARalpha in mediating the effects of CFAM on the activity of
acyl-CoA oxidase ( ACO ) and omega-laurate hydroxylase ( CYP4A ), the regulation of which is known to be dependent on the PPARalpha
Ahmed et al., Circ Res 2006
:
Moreover, HDL stimulation induced expression of the canonical PPARalpha-target gene
acyl-CoA-oxidase ( ACO ) in a
PPARalpha dependent manner in ECs
Krey et al., Mol Endocrinol 1995
:
We identified several functional cis acting elements present in the promoter of the ACO gene and established that
PPAR dependent as well as PPAR independent mechanisms can
activate the
ACO promoter in these cells
Belury et al., Toxicol Appl Pharmacol 1998
:
The
involvement of
PPAR in the peroxisome proliferator mediated induction of fatty acid metabolizing genes such as
acyl-CoA oxidase ( ACO ) , fatty acid binding protein (FABP), and cytochrome P450IVA1 ( CYP4A1 ) has been clearly demonstrated