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IL6 — SKP1
Text-mined interactions from Literome
Huang et al., Blood 1999
:
However,
interleukin-5 (IL-5) alone sustained survival of TF-1 cells and
required costimulation of
SCF for optimal proliferation
Gyotoku et al., Arch Dermatol Res 2001
:
Some
IL-6 family cytokines
enhanced the production of
stem cell factor (SCF) , a potent mast cell growth factor, from NIH/3T3 fibroblasts, but the amount of SCF produced by NIH/3T3 fibroblasts was not paralleled by the mast cell growth-enhancement induced by the IL-6 family cytokines
Ren et al., J Clin Invest 2003
:
In vitro studies using primary mouse hepatocytes demonstrate that
SCF causes hepatocyte proliferation and is
induced by
IL-6 and that treatment with anti-SCF antibodies inhibits IL-6 induced hepatocyte proliferation
Bouchelouche et al., J Urol 2006
:
Furthermore, IL-1beta and tumor necrosis factor-alpha alone induced significant release of MCP-1, IL-6 and
SCF but in combination with IL-4 or IL-13 it
induced greater secretion of MCP-1,
IL-6 and SCF
Neta et al., J Immunol 1994
:
SCF , unlike IL-1 does not
induce hemopoietic CSFs and
IL-6 or gene expression of a scavenging mitochondrial enzyme manganese superoxide dismutase in the bone marrow, suggesting that SCF and IL-1 radioprotect by distinct pathways
Nakahata et al., Cancer Chemother Pharmacol 1996
:
The sIL-6R-IL-6 complex, but not sIL-6R or
IL-6 alone, in the
presence of
stem-cell factor (SCF) produced dramatic increases in the populations of various cell lineages, including erythroid cells and various hematopoietic progenitors, in suspension culture
Huss et al., Exp Mol Pathol 1995
:
While differentiating, these cells start to express CD34 and DR. Differentiation is
induced by
stem cell factor (SCF) , while
interleukin-6 (IL-6) inhibits differentiation, but promotes proliferation
Tisdale et al., Blood 1998
:
Stem cell factor (SCF)/granulocyte colony stimulating factor ( G-CSF ) -mobilized and CD34 enriched PB cells were divided into two equal aliquots and transduced with one of two retroviral vectors carrying the neomycin-resistance gene ( neo ) for 4 days in the
presence of interleukin-3 (IL-3),
IL-6 , and SCF in the first 5 animals, IL-3/IL-6/SCF/Flt-3 ligand (FLT) in 2 subsequent animals, or
IL-3/IL-6/SCF/FLT plus an autologous stromal monolayer ( STR ) in the final 2