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EPHB2 — MAP3K7
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Hammaker et al., J Immunol 2004
(Arthritis, Rheumatoid...) :
Of interest, MEKK1 immunoprecipitates from IL-1 stimulated FLS appeared to activate c-Jun through the JNK pathway and
TAK1 activation of c-Jun was
dependent on JNK,
ERK , and p38
Windheim et al., Biochem J 2007
:
We also show that MDP activates
ERK1 ( extracellular-signal regulated kinase 1 ) /ERK2 and p38alpha MAPK in human peripheral-blood mononuclear cells and that the activity of both MAPKs and
TAK1 are
required for MDP induced signalling and production of IL-1beta and TNFalpha in these cells
Hebron et al., Br J Haematol 2013
(Multiple Myeloma...) :
In myeloma tumour cells,
MAP3K8 acts as mitogen induced MAP3K in mitosis and is
required for TNFa mediated
ERK activation