Gene interactions and pathways from curated databases and text-mining

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CAPN2 — EPHB2

Text-mined interactions from Literome

Glading et al., J Biol Chem 2001 (MAP Kinase Signaling System) : Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling
Glading et al., Mol Cell Biol 2004 (MAP Kinase Signaling System) : We now show that ERK directly phosphorylates and activates m-calpain both in vitro and in vivo
Kawashima et al., Endocrinology 2012 : During EGF-like factor induction of COC expansion in culture, calpain activity was increased by ERK1/2 and intracellular Ca ( 2+ ) signaling pathways
Briz et al., J Neurosci 2013 : BDNF treatment increased phosphorylation of both Akt and ERK , but only the effect on Akt was blocked by calpain inhibition