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IL6 — TNC
Text-mined interactions from Literome
Kuriyama et al., Hepatology 2011
(Reperfusion Injury) :
The lack of
Tnc expression
resulted in impaired leukocyte recruitment and decreased expressions of interleukin (IL)-1ß,
IL-6 , and CXCL2 after liver reperfusion
Maqbool et al., Matrix Biol 2013
:
ECM-regulatory matricellular proteins are synthesized by several myocardial cell types including CF. We investigated the effects of pro-inflammatory cytokines on matricellular protein expression in cultured human CF. cDNA array analysis of matricellular proteins revealed that
interleukin-1a ( IL-1a, 10ng/ml, 6h ) down-regulated connective tissue growth factor ( CTGF/CCN2 ) mRNA by 80 % and
up-regulated tenascin-C (TNC) mRNA levels by 10-fold in human CF, without affecting expression of thrombospondins 1-3, osteonectin or osteopontin