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CHGA — IFNG

Text-mined interactions from Literome

Pavlovic et al., Eur Cytokine Netw 1999 : IFN-gamma decreased the IL-1beta induced SPI-3 expression in wt islets or beta-cells, but induced a 5-fold increase in the expression of this mRNA in IRF-1-/- islets cells, suggesting that IRF-1 mediates an inhibitory effect of IFN-gamma on SPI-3 expression
Hamerman et al., J Immunol 2002 (Bacterial Infections) : The cytokine IFN-gamma also induces spi2a expression in macrophages, and this induction is synergistic with bacterial products ... Whereas spi2a was induced by either bacterial products or IFN-gamma , ISG15 was induced only by bacterial products
Kordula et al., Biochem J 1995 : Thus the induction of the SPI-3 gene by IFN gamma correlates with the binding of Stat1 to a specific element which, in turn, binds Stat3 in response to interleukin 6