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IRF6 — PECAM1
Text-mined interactions from Literome
Rui et al., J Immunol 2007
:
However, the
role and the mechanisms of
PECAM-1 in the regulation of TLR4 mediated
LPS response in macrophages remain unclear ... Taken together with the data that
PECAM-1 is constitutively expressed in macrophages and its expression is
up-regulated by
LPS stimulation, PECAM-1 might function as a feedback negative regulator of LPS inflammatory response in macrophages
Hebeda et al., Clin Exp Immunol 2011
(Inflammation) :
Here, the molecular mechanism by which NO regulates
lipopolysaccharide (LPS) induced endothelial
PECAM-1 expression and the role of interleukin (IL)-10 on this control was investigated ... Supernatant of LPS stimulated lymphocytes obtained from L-NAME treated rats, which contained higher levels of IL-10, reduced
LPS induced
PECAM-1 expression by endothelial cells, and this reduction was reversed by adding the anti-IL-10 monoclonal antibody