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MAPK3 — MOK
Text-mined interactions from Literome
Zill et al., Biochem Biophys Res Commun 2003
:
RAGE mediated
MAPK activation by food derived AGE and non-AGE products
Cecil et al., J Immunol 2005
(Hypertrophy...) :
Last, via transfection of dominant negative RAGE and dominant negative MAPK kinase 3, we demonstrated that S100A11 induced chondrocyte type X collagen expression was dependent on
RAGE mediated p38
MAPK pathway
activation
Origlia et al., J Neurosci 2008
:
Moreover, Abeta mediated enhancement of p38
MAPK phosphorylation in cortical neurons was
reduced by blocking antibodies to
RAGE ... Together, our results indicate that Abeta impairs LTP in the entorhinal cortex through neuronal
RAGE mediated activation of p38
MAPK
Spiekerkoetter et al., Circ Res 2009
:
Phosphorylation of extracellular signal regulated kinase is induced by both ligands and is required for motility by inducing matrix metalloproteinase 2 activity, but
phospho-extracellular signal regulated kinase 1/2 is
blocked by
anti-RAGE and not by BMPRII short interference RNA
Zong et al., Diabetologia 2010
(Diabetes Mellitus, Experimental...) :
Activation of mitogen activated protein kinase (
MAPK ) by
RAGE was determined by western blotting
Bianchi et al., J Biol Chem 2011
(Encephalitis) :
We show here that high S100B stimulates murine microglia migration in Boyden chambers via
RAGE dependent activation of Src kinase, Ras, PI3K,
MEK/ERK1/2 , RhoA/ROCK, Rac1/JNK/AP-1, Rac1/NF-?B, and, to a lesser extent, p38 MAPK
Li et al., Neurobiol Aging 2012
(Alzheimer Disease...) :
In SK-NS-H cells, upregulation of AGEs receptor (
RAGE ), inhibition of Akt, and
activation of glycogen synthase kinase-3 ( GSK-3 ),
Erk1/2 , and p38 were observed after treatment with AGEs
de Bittencourt Pasquali et al., Cell Signal 2013
(Lung Neoplasms) :
The effect of retinol on
RAGE was
mediated by p38
MAPK activation, as blockade of p38 with PD169316 ( 10µM ), SB203580 ( 10µM ) or siRNA to either p38a ( MAPK14 ) or p38ß ( MAPK11 ) reversed the effect of retinol on RAGE