Chanchevalap et al., Nucleic Acids Res 2006
:
Importantly, suppression of KLF5 by small interfering RNA ( siRNA ) resulted in a reduction in p50 and p65 subunit mRNA levels and NF-kappaB DNA binding activity in response to LPS
Lin et al., Arterioscler Thromb Vasc Biol 2006
:
Mechanistically, KLF2 inhibits PAR-1 expression and, as a consequence, thrombin mediated nuclear factor kappaB (NF-kappaB) nuclear accumulation and DNA binding
Das et al., Proc Natl Acad Sci U S A 2006
(Atherosclerosis...) :
Mechanistically, KLF2 inhibits the transcriptional activity of both NF-kappaB and activator protein 1, in part by means of recruitment of transcriptional coactivator p300/CBP associated factor