Gehler et al., J Neurosci 2004
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Furthermore, BDNF promotes the activation of ADF/cofilin by reducing the phosphorylation of ADF/cofilin
Chen et al., J Neurobiol 2006
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Cdc42 participates in the regulation of ADF/cofilin and retinal growth cone filopodia by brain derived neurotrophic factor ... We previously showed that the neurotrophin BDNF regulates filopodial dynamics on growth cones of retinal ganglion cell axons through activation of the actin regulatory proteins ADF and cofilin by inhibiting a RhoA dependent pathway that phosphorylates ( inactivates ) ADF/cofilin Tong et al., J Neurosci 2012
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Using rat organotypic hippocampal cultures, we found that IL-1ß suppressed BDNF dependent regulation of Arc and phosphorylation of cofilin and cAMP response element binding protein ( CREB ), a transcription factor regulating Arc expression