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AKT1 — WNK1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Vitari et al., Biochem J 2004
(Hypertension...) :
Our study provides strong pharmacological and genetic evidence that
PKB mediates the phosphorylation of
WNK1 at Thr-60 in vivo
Sale et al., Biochemistry 2006
:
Role of
protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin,
WNK1 , and ATP citrate lyase ...
Role of
protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin,
WNK1 , and ATP citrate lyase
Parhar et al., Mol Cell Biochem 2007
:
Similarly, over-expression of PDK1 but not
PKB resulted in promotion of
p65 DNA binding
Nakamura et al., Rheumatol Int 2007
(Sjogren's Syndrome) :
Chemical inhibition of
PI3K-Akt by LY294002/wortmannin did not
affect EGF mediated NF-kappaB
p65 nuclear translocation ; and NF-kappaB inhibition by Bay 11-7082 did not suppress Akt phosphorylation
Wang et al., J Biol Chem 2010
:
Selective knockdown of EP2 or ectopic expression of EP3 blocks PKA- and
PI3-K/Akt dependent
p65 activation and markedly diminishes shear induced IL-6 expression
Harbrecht et al., Am J Physiol Gastrointest Liver Physiol 2012
(MAP Kinase Signaling System) :
NF-?B induces iNOS expression and can be
regulated by
Akt , but insulin had no effect on cytokine mediated I?Ba levels or NF-?B
p65 translocation