Kato et al., J Allergy Clin Immunol 2005
:
Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1 : biochemical skin barrier against mite cysteine proteases
Ogawa et al., Int Arch Allergy Immunol 2008
(Dermatitis, Atopic) :
Cystatin A is a skin derived dominant inhibitor against proteolytic activity of major mite allergens, Der f 1 and Der p 1, and blocks the upregulation of IL-8 release from human keratinocytes stimulated with the allergens