Gene interactions and pathways from curated databases and text-mining

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BMP2 — IL1B

Text-mined interactions from Literome

Fukui et al., J Bone Joint Surg Am 2003 (Osteoarthritis) : In cartilage explant cultures, IL-1beta and TNF-alpha increased BMP-2 levels both intracellularly and extracellularly
Andriamanalijaona et al., J Periodontol 2006 (Hemolysis) : Effect of interleukin-1beta on transforming growth factor-beta and bone morphogenetic protein-2 expression in human periodontal ligament and alveolar bone cells in culture : modulation by avocado and soybean unsaponifiables ... In this study, we investigated the in vitro effect of avocado and soya unsaponifiables ( ASU ) on the expression of TGF-beta1, TGF-beta2, and bone morphogenetic protein-2 (BMP-2) by human periodontal ligament (HPL) and human alveolar bone ( HAB ) cells in the presence of IL-1beta
Sandell et al., Osteoarthritis Cartilage 2008 (Arthritis) : In the presence of IL-1beta , FGF-18 increased expression of ADAMTS-4, aggrecan, BMP-2 , COL2A1, CCL3, CCL4, CCL20, CXCL1, CXCL3, CXCL6, IL-1beta, IL-6, and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Elshaier et al., Arthritis Rheum 2009 (MAP Kinase Signaling System) : The effect of IL-1beta on BMP receptors was studied by reverse transcription-polymerase chain reaction and flow cytometry
Nakase et al., Bone 1997 : The modulatory effects of interleukin (IL)-1 beta and tumor necrosis factor (TNF)-alpha on bone morphogenetic protein (BMP)-2- and -4-induced alkaline phosphatase (ALP) activity were examined in cultures of mouse MC3T3-E1 osteoblastic cells