Gene interactions and pathways from curated databases and text-mining

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ADIPOQ — CASP2

Text-mined interactions from Literome

Jung et al., FEBS J 2009 : Adiponectin reduced palmitate- and thapsigargin induced activation of caspase-3 and cell death in a dose dependent manner
Saxena et al., Gastroenterology 2010 (Carcinoma, Hepatocellular...) : Adiponectin increased apoptosis of HCC cells through activation of caspase-3 ... Adiponectin increased phosphorylation of c-Jun-N-terminal kinase (JNK) and inhibition of c-Jun-N-terminal kinase-phosphorylation inhibited adiponectin induced apoptosis and caspase-3 activation
Qiu et al., Age (Dordrecht, Netherlands) 2011 : Adiponectin reduced the level of reactive oxygen species, attenuated apoptotic cell death, and also suppressed activation of caspase-3 induced by KA