Gene interactions and pathways from curated databases and text-mining

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C9ORF3 — PDCD4

Text-mined interactions from Literome

Debatin et al., Blood 1993 (Leukemia, T-Cell) : Triggering of APO-1 by the monoclonal antibody anti-APO-1 induces programmed cell death ( apoptosis ) in APO-1 expressing cells
Bargou et al., Int J Cancer 1995 (Breast Neoplasms) : In contrast to malignant cell lines, which express low levels of bax-alpha, non-malignant epithelial cell lines displaying high amounts of bax-alpha were highly sensitive to induction of programmed cell death by both serum starvation and APO-1/fas ( CD95 ) triggering
Deiss et al., EMBO J 1996 : Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
Sytwu et al., Immunity 1996 (Lymphoproliferative Disorders) : The roles of Fas/APO-1 ( CD95 ) and TNF in antigen induced programmed cell death in T cell receptor transgenic mice
Egle et al., Br J Haematol 1997 (Multiple Myeloma) : We studied eight myeloma cell lines for the presence of Bcl-2, which inhibits apoptosis, of Bax, which counteracts Bcl-2, of Bcl-x ( L ) and Bcl-x ( S ), which act in an anti- and pro-apoptotic fashion, respectively, and of Apo-1/Fas , which induces programmed cell death , when activated by the Apo-1/Fas ligand or the relevant monoclonal antibody ( mab )
Huang et al., Immunity 1997 : Fas/APO-1 ( CD95 ) ligation activates programmed cell death , a cellular process that plays an important role in the maturation of the host immune response