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EIF4E — FGF2
Text-mined interactions from Literome
Tao et al., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2004
(Laryngeal Neoplasms) :
The protein expression of
eIF4E , eIF4G, bFGF and VEGF were significantly inhibited by elemene ; and the mRNA expression of
bFGF and VEGF were
inhibited either
Oridate et al., Cancer Biol Ther 2005
(Carcinoma, Squamous Cell...) :
siRNA mediated decrease of
eIF4E has
led to decreases in the expression of CCND1,
basic fibroblast growth factor and vascular endothelial growth factor
Dong et al., Breast Cancer Res Treat 2009
(Breast Neoplasms) :
The downregulation of
eIF4E expression significantly
reduced the levels of VEGF,
FGF-2 and cyclinD1 expression, suppressed cell growth, induced cell cycle arrest in G ( 0 ) /G ( 1 ) phase and subsequent apoptosis by activating caspase 3 in MCF-7 cells
Chang et al., Cancer Gene Ther 2013
:
Reduction of
eIF4E by overexpression of 4E-BP1
resulted in suppression of cap dependent protein expression of
basic fibroblast growth factor ( bFGF or FGF-2 ) and vascular endothelial growth factor ( VEGF )