Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ADRBK1 (GRK2)
→
MAPK1
(increases, MAPK1 Activity, GRK2 Activity)
Evidence: ERK1/2 activation via adenosine A3 receptors may be an important mechanism for the regulation of the receptor itself, regulating its desensitisation and internalisation in a GRK2-dependent manner [138].