Gene interactions and pathways from curated databases and text-mining

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NPY6R — TYR

Text-mined interactions from Literome

Salazar et al., J Biol Chem 2001 : In contrast to the results obtained with fibronectin, PP-2 did not prevent FAK Tyr-397 phosphorylation stimulated by bombesin at a concentration ( 10 micrometer ) that suppressed bombesin induced FAK Tyr-577 phosphorylation ... Similarly, PP-2 did not prevent Tyr-397 phosphorylation in Swiss 3T3 cells stimulated with other G protein coupled receptor agonists including vasopressin, bradykinin, endothelin, and lysophosphatidic acid
Sato et al., Genes Cells 2003 : The phosphorylation of Tyr 845 can be inhibited by PP2 , but not by AG1478, and is associated with Src activation and Stat 3/5 phosphorylation, but not with MAP ( mitogen activated protein ) kinase phosphorylation
Chang et al., Mol Pharmacol 2004 : The Tyr701 phosphorylation of signal transducer and activator of transcription 1 ( STAT1 ) induced by interferon-gamma (IFN-gamma) and 12-O-tetradecanoylphorbol 13-acetate ( TPA ) was inhibited by the protein kinase C ( PKC ) inhibitor staurosporine, the tyrosine kinase inhibitor herbimycin, or the Src kinase inhibitor PP2
Wu et al., Cell Signal 2005 : In Swiss 3T3 cells, PP2 enhanced Tyr-418 phosphorylation after 1 min of bombesin stimulation, while in IEC-18 cells, PP2 increased Ang II-stimulated Tyr-418 phosphorylation at all times tested
Mizutani et al., Mol Endocrinol 2006 (Leydig Cell Tumor...) : The LHR mediated phosphorylation of FAK-Tyr576 is readily inhibited by PP2 ( a pharmacological inhibitor of SFKs ) and by dominant negative mutants of SKFs
Chaturvedi et al., Am J Physiol Cell Physiol 2007 (Mechanotransduction, Cellular) : PP2 also blocked strain induced phosphorylation of FAK-Tyr ( 576 ) and ERK-Thr ( 202 ) /Tyr ( 204 ) but not FAK-Tyr ( 397 )