◀ Back to NPY6R
NPY6R — TYR
Text-mined interactions from Literome
Salazar et al., J Biol Chem 2001
:
In contrast to the results obtained with fibronectin,
PP-2 did not
prevent FAK
Tyr-397 phosphorylation stimulated by bombesin at a concentration ( 10 micrometer ) that suppressed bombesin induced FAK Tyr-577 phosphorylation ... Similarly,
PP-2 did not
prevent Tyr-397 phosphorylation in Swiss 3T3 cells stimulated with other G protein coupled receptor agonists including vasopressin, bradykinin, endothelin, and lysophosphatidic acid
Sato et al., Genes Cells 2003
:
The phosphorylation of
Tyr 845 can be
inhibited by
PP2 , but not by AG1478, and is associated with Src activation and Stat 3/5 phosphorylation, but not with MAP ( mitogen activated protein ) kinase phosphorylation
Chang et al., Mol Pharmacol 2004
:
The
Tyr701 phosphorylation of signal transducer and activator of transcription 1 ( STAT1 ) induced by interferon-gamma (IFN-gamma) and 12-O-tetradecanoylphorbol 13-acetate ( TPA ) was
inhibited by the protein kinase C ( PKC ) inhibitor staurosporine, the tyrosine kinase inhibitor herbimycin, or the Src kinase inhibitor
PP2
Wu et al., Cell Signal 2005
:
In Swiss 3T3 cells, PP2 enhanced Tyr-418 phosphorylation after 1 min of bombesin stimulation, while in IEC-18 cells,
PP2 increased Ang II-stimulated
Tyr-418 phosphorylation at all times tested
Mizutani et al., Mol Endocrinol 2006
(Leydig Cell Tumor...) :
The LHR mediated phosphorylation of
FAK-Tyr576 is readily
inhibited by
PP2 ( a pharmacological inhibitor of SFKs ) and by dominant negative mutants of SKFs
Chaturvedi et al., Am J Physiol Cell Physiol 2007
(Mechanotransduction, Cellular) :
PP2 also
blocked strain induced phosphorylation of
FAK-Tyr ( 576 ) and ERK-Thr ( 202 ) /Tyr ( 204 ) but not FAK-Tyr ( 397 )